منابع مشابه
Hypertrophic cardiomyopathy: diagnosis, risk stratification and treatment.
mon inherited cardiomyopathy, occurring in about 1 in 500 individuals. The first gene mutation for this condition was identified in a large French Canadian family cohort in 1989. Clinical presentation typically includes left ventricular hypertrophy in the absence of abnormal loading conditions, such as hypertension or aortic stenosis. Hypertrophic cardiomyopathy has come to public recognition i...
متن کاملRisk stratification in hypertrophic cardiomyopathy: fact or fiction?
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac muscle disease that affects sarcomeric proteins, resulting in severe hypertrophy, myofibrillar disorganization, and enhanced interstitial fibrosis. The disease is often familial, with autosomal-dominant transmission. More than 100 different mutations in 10 genes that encode sarcomeric proteins have been described (1–3). Hypertrophy typic...
متن کاملRisk stratification in nonischemic dilated cardiomyopathy: Current perspectives.
The clinical goals of risk stratification of sudden death are to identify subjects who are at high risk of, and eventually to reduce the incidence of, sudden death. Numerous studies have described risk stratification techniques for serious cardiac events in patients following myocardial infarction. However, relatively little information is available regarding nonischemic dilated cardiomyopathy....
متن کاملRisk stratification and prevention of sudden death in hypertrophic cardiomyopathy.
Sudden unexpected death, often occurring in young, asymptomatic patients, is the most devastating facet of the natural history of hypertrophic cardiomyopathy, and appears to be the consequence of primary ventricular tachyarrhythmias arising in an electrically unstable myocardial substrate characterized by disorganized cellular architecture, ischemia, cell death, and replacement scarring. Althou...
متن کاملNoninvasive Arrhythmia Risk Stratification in Idiopathic Dilated Cardiomyopathy
Background—Arrhythmia risk stratification with regard to prophylactic implantable cardioverter-defibrillator therapy is a completely unsolved issue in idiopathic dilated cardiomyopathy (IDC). Methods and Results—Arrhythmia risk stratification was performed prospectively in 343 patients with IDC, including analysis of left ventricular (LV) ejection fraction and size by echocardiography, signal-a...
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ژورنال
عنوان ژورنال: European Journal of Preventive Cardiology
سال: 2020
ISSN: 2047-4881,2047-4873
DOI: 10.1177/2047487320961898